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Event Symposium on Evolutionary Systems Biology by Laurence Loewe, last updated: Jul 11, 2009 09:37 AM
The 2009 congress of the European Society for Evolutionary Biologists (ESEB) will host a symposium on evolutionary systems biology. Look forward to an exciting series of talks that explore how systems biology might contribute to answer some of the most difficult problems in evolutionary biology.
Page Quick start for newcomers by Laurence Loewe, last updated: Jul 11, 2009 08:21 AM
This page describes how easy it is to start contributing CPU-power to evolution@home.
Page Contribute by Laurence Loewe, last updated: Jul 11, 2009 08:07 AM
How you can help.
Image Distribution of deleterious mutational effects (DDME) by Laurence Loewe, last updated: Jul 11, 2009 07:48 AM
Three different possible types of DDMEs as computed from DNA diversity data in the fruitflies Drosophila miranda and D. pseudoobscura. The lognormal distribution is the only one that can explain the observed numbers of lethal mutations (right axis). The normal DDME could not even explain the observed diversity data (best possible fit shown). The vertical grey line marks the border to effective neutrality (Nes = 0.5 with Ne = 837000). For more details, see Loewe & Charlesworth (2006, http://www.journals.royalsoc.ac.uk/openurl.asp?genre=article&issn=1744-9561&volume=2&issue=3&spage=426).
Image Evolutionary theory unifies Biology by Laurence Loewe, last updated: Jul 11, 2009 07:47 AM
Evolution as a theory is general enough to ultimately include every field in biology (see http://www.biomedcentral.com/1752-0509/3/27).
Image Organization of the human genome by Laurence Loewe, last updated: Jul 11, 2009 07:43 AM
This overview shows all chromosomes of the human genome as seen in the Ensembl Genome browser. Genome browsers allow zooming in until the actual sequence of individual genes can be seen (see http://www.ensembl.org/Homo_sapiens/).
Image The structure of DNA is a double helix by Laurence Loewe, last updated: Jul 11, 2009 07:42 AM
DNA is like the paper for a text written with the 4 letters A, T, C and G. The structure of DNA is a double helix, where Adenine pairs with Thymine and Cytosine pairs with Guanine. This knowledge started the molecular biology revolution in 1953. Today many biologists do 'sequencing', i.e. read DNA sequences, routinely. For detail on this molecule see http://www.imb-jena.de/cgi-bin/ImgLib.pl?CODE=1bna.
Image Structure of a protein by Laurence Loewe, last updated: Jul 11, 2009 07:41 AM
The molecular structure of the protein that allows mammals to see by transforming the light in the eye into a noticeable signal. The various secondary structure elements (e.g. the red alpha helices) can be seen clearly. For more details see http://www.imb-jena.de/cgi-bin/ImgLib.pl?CODE=1f88.
Image The Ribosome by Laurence Loewe, last updated: Jul 11, 2009 07:41 AM
The ribosome is a hugely complicated molecular machine that translates mRNA into amino acid sequences. This picture shows only a part of the molecular structure of a ribosome. For more details see http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=2b64.
Page Why evolution matters by Laurence Loewe, last updated: Jul 11, 2009 07:41 AM
Evolutionary biology touches many topics of practical importance. It also investigates some fascinating questions. Here is a very selective shortlist.
Page EvoHo by Laurence Loewe, last updated: Jul 11, 2009 07:17 AM
Introduction to evolution@home
Page EvRe by Laurence Loewe, last updated: Jul 11, 2009 06:59 AM
Introduction to evolutionary-research, the scientific research initiative.
Page Intro by Laurence Loewe, last updated: Jul 11, 2009 05:38 AM
Introduction to evolution@home (EvoHo) and evolutionary-research (EvRe).
Folder Teaching by Laurence Loewe, last updated: Jul 02, 2009 09:28 AM
Homepages of courses that teach about details of evolution.
Page Other introductions to evolution by Laurence Loewe, last updated: Jul 02, 2009 09:20 AM
Links to other pages that give introductions to evolutionary theory that are easy to understand.
Page Mutations in proteins, genes & genomes by Laurence Loewe, last updated: Jul 02, 2009 09:15 AM
A very short introduction to current knowledge on what mutations do to the structure of genomes, genes and proteins.
Page Introduction by Laurence Loewe, last updated: Jul 02, 2009 09:14 AM
The engine of evolution is the combination of all forces that drive evolution. These pages take an introductory look at them.
Folder The engine of evolution by Laurence Loewe, last updated: Jul 02, 2009 09:14 AM
Evolution is driven by powerful forces of nature. These pages are a short introduction to the various forces that govern biological evolution.
Page The principle of Muller’s ratchet by Laurence Loewe, last updated: Jul 02, 2009 07:56 AM
The main effect of Muller’s ratchet is the accumulation of slightly harmful DNA changes in a population over many generations. This can lead to the extinction of species and is thus of considerable biological interest.
Page How to quantify effects of Muller's ratchet by Laurence Loewe, last updated: Jul 02, 2009 07:45 AM
Evolution@home has compiled the largest existing database of Muller's ratchet simulation results. This allows quantifications of the threat of extinction and other aspects of Muller's ratchet with unprecedented accuracy. Depending on what you know about your favorite organism, evolution@home results might help to work out what the ratchet does there.
 
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