Personal tools
You are here: Home People Loewe, Laurence Teaching Evolutionary Genetics

Evolutionary Genetics - Course Webpage 2007

This is the course webpage of the 2007 Evolutionary Genetics MSc module at the University of Edinburgh. It was organised by Laurence Loewe as part of the MSc in Quantitative Genetics and Genome Analysis. All further details are on these pages.

 

Lectures for 2007 are over

A similar module will run again next year. 
For details, see the website.

Location: Ashworth Labs, Kings Buildings
University of Edinburgh, Scotland, UK

If you are interested in taking this course next year, 
please see the course website.

 

Topics

How can population genetical theory be applied to the study of natural populations? What is important in building evolutionary models? What can we infer from DNA sequence diversity found in populations? Can we detect evidence for population structure in genes? What can we infer about selection and inbreeding in natural populations? This course will cover various approaches to answer these questions using classic and state-of-the-art methods. For more details on the topics of this course and recommended reading, see here.

 

Assessment via Essays and Exam

Those of you who need the 20 points that can be earned by enrolling formally in this course will want to know that 6 points will come from 3 incourse assessments (see the afternoon practicals). 7 points come from a 90 min closed book exam and another 7 points come from a 90 min open book exam. More details will be sent to graduates who enrol.

If you are interested in taking this course next year, 
please see the course website.

 

Timetable

The course runs for 4 weeks (26 Feb 2007 - 23 Mar 2007) and is completely based in the Ashworth Labs, Kings Buildings, University of Edinburgh. Overview of teaching times:

  • Lectures start at 9.30 each morning (except Wednesdays) and will go on for 1-2 hours (max until 12.00). All lectures are either in Honours Room 1 or 2 in the Ashworth Labs. In addition, there will be 2 lectures on Wednesday 21 March 2007 (12-1 + 2-3pm, same place)
  • Guest seminars on Tuesday (12-1pm) are especially organized for this course to help broaden the horizon. Location: Honours Room 1 or 2 in the Ashworth Labs.
  • To help broaden the horizon further you can join a number of 'Clubs':
    • Genetics Journal Club (Thursday, 1-2pm, in Ashworth2 SeminarRoom B/C),
    • Quantitative Genetics Journal Club (Wednesday, 1-2pm, in Ashworth2 SeminarRoom B/C) and
    • IEB seminar (Wednesday, 4-5pm, Ashworth Lecture Theater 3)
  • Computer exercises ('Pract') are from 2-4pm on the first three Fridays and in addition on Monday 12 March, Monday 19 March, Tuesday 20 March 2007 and Thursday 22 March 2007. These help gain experience with the practical details of working on topics related to the lectures. Location: Computing Room 110, Darwin Building.

 

Date (2007)  Time       
Room 
Event    
Topic Lecturer






Mo 26 Feb
9.30-
HR1
Lecture
Modeling foundations
LL
Tu 27 Feb
9.30- HR1 Lecture Modeling evolution
LL
Tu 27 Feb
12-1pm
HR1
Guest
Methods of simulation
SK
We 28 Feb
1-2pm
B/C
Club
Quantitative Genetics Journal Club

We 28 Feb
4-5pm
LT3
Club
Institute Seminar (IEB)

Th 1 Mar
9.30-
HR2
Lecture
Coalescent foundations
LL
Th 1 Mar
1-2pm B/C Club Genetics Journal Club
Fr 2 Mar
9.30- HR2 Lecture Coalescent applications
LL
Fr 2 Mar
2-4pm
D110 Pract
Coalescent simulations exercise
LL






Mo 5 Mar
9.30- HR1
Lecture
Population structure and drift
LL
Tu 6 Mar
9.30- HR1 Lecture Population structure and selection
LL
Tu 6 Mar
12-1pm
HR1
Guest
Fine scale population structure
JP
We 7 Mar
1-2pm B/C Club Quantitative Genetics Journal Club
We 7 Mar
4-5pm LT3 Club Institute Seminar (IEB)
Th 8 Mar
9.30- HR2 Lecture Testing for selection (1)
LL
Th 8 Mar
1-2pm B/C Club Genetics Journal Club
Fr 9 Mar
9.30- HR2 Lecture Detecting Selection
DC
Fr 9 Mar
2-4pm
D110 Pract
Population structure estimation
LL






Mo 12 Mar
9.30- HR1 Lecture Testing for selection (2)
LL
Mo 12 Mar
2-4pm D110 Pract
Searching for selected genes
LL
Tu 13 Mar
9.30- HR1 Lecture Balancing selection
DC
Tu 13 Mar
12-1pm
HR1 Guest Selective constraints
PK
We 14 Mar
1-2pm B/C Club Quantitative Genetics Journal Club
We 14 Mar
4-5pm LT3 Club Institute Seminar (IEB)
Th 15 Mar
9.30- HR2 Lecture Phylogenetics 1
ALB
Th 15 Mar
1-2pm B/C Club Genetics Journal Club
Fr 16 Mar
9.30- HR2 Lecture Phylogenetics 2
ALB
Fr 16 Mar
2-4pm D110 Pract MEGA Practical
ALB






Mo 19 Mar
9.30-
HR1 Lecture Animal models 1+2 LK+AW
Mo 19 Mar
2-4pm D110 Pract Quantitative genetics
LK+AW
Tu 20 Mar
9.30- HR1 Lecture
Animal models 3+4 (not mandatory for MSc) LK+AW
Tu 20 Mar
2-4pm D110 Pract Quantitative genetics (not mandatory for MSc) LK+AW
We 21 Mar
12-1pm
HR1 Lecture
Selection and microevolution 1
LK+AW
We 21 Mar
1-2pm B/C Club
Quantitative Genetics Journal Club
We 21 Mar
2-3pm
HR1
Lecture
Selection and microevolution 2
LK+AW
We 21 Mar
4-5pm LT3 Club
Institute Seminar (IEB)
Th 22 Mar
9.30- HR2 Lecture Inbreeding depression 1+2 JP
Th 22 Mar
12-1pm HR2 Guest
Understanding the genetic architecture of complex trait in natural populations using QTL mapping
DB
Th 22 Mar
1-2pm B/C Club Genetics Journal Club
Th 22 Mar
2-4pm D110 Pract
Inbreeding depression
JP






Lectures are delivered by
Dario Beraldi (DB), Deborah Charlesworth (DC), Peter Keightley (PK), Sarah Knott (SK), Loeske Kruuk (LK), Laurence Loewe (LL), Andy Leigh-Brown (ALB), Josephine Pemberton (JP), Alastair Wilson (AW).

Rooms are at Ashworth, Kings Buildings, unless noted otherwise:
HR1 or HR2 = Honours Room 1 or 2; B/C = SeminarRoom B/C; LT3 = Lecture Theater 3; D110 = Computing Room 110 in the Darwin Building; Bioinformatics lectures are external.

 

Document Actions